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How to Make a Medicinal Mushroom Triple Extract

Updated: Aug 18, 2022

Below, you will find a simple step-by-step guide to making your own medicinal mushroom triple extract. Please understand that this is a simplified version and that our products do not use the medicinal mushroom triple extract process.

To learn about our current extraction processes, read our article Medicinal Mushroom Extractions: A Primer on Our Process, dive into the details of why we use a Soxhlet in Soxhlet Extractor: Why We Do What We Do, and check out our methods with our simplified How to Use a Soxhlet Extractor guide.

  1. Grow or purchase U.S. grown medicinal mushrooms, preferably from your local mushroom farmer

  2. Dehydrate mushrooms until cracker dry (typically about 48 hours for medicinal mushrooms Lion’s Mane and 24 hours for polypores like Turkey Tail and Reishi)

  3. Pulverize your dried medicinal mushrooms into a powder or ¼-inch chunks

  4. Cover your dried medicinal mushrooms with 190 proof ethanol alcohol (or organic cane alcohol if you want to be like us) and let sit for 24 to 48 hours

  5. Strain the medicinal mushroom powder from the alcohol, then press the medicinal mushroom powder to drain out any residual alcohol, collecting the alcohol in a glass jar or other glass container

  6. Label this glass container ETOH Extract #1

  7. Place your medicinal mushroom powder into a stock pot or crockpot, cover with water, and simmer for 2 to 12 hours

  8. Place your medicinal mushroom powder—water mixture in a glass jar or container, leaving the container ⅓ empty

  9. Fill the remaining ⅓ of the jar with ETOH Extract #1

  10. Let sit for 4-8 weeks, shaking the container daily

  11. Strain the medicinal mushroom powder from the jar, collecting the water—alcohol mixture in a glass jar or container

  12. Press the powder to drain any residual solvent, collect this remaining solvent, combine with water—alcohol mixture from Step 11

  13. Label and enjoy! This is your shelf stable medicinal mushroom triple extract at about 30% ABV

When done correctly, this medicinal mushroom triple extract should contain the volatile compounds, polysaccharides, triterpenes, phenolic compounds, and fatty acids found in medicinal mushrooms.

We want to thank Dr. Anna Sitkoff, a licensed naturopathic doctor, medicinal mushroom educator, and author of the medicinal mushrooms chapter in The Textbook of Natural Medicine, for this medicinal mushrooom triple extract methodology as seen on her blog Reishi & Roses.

DISCLAIMER: This article is for informational and educational purposes only. Mindfull Mycology assumes no risk or liability for any actions or ingestion of products related to the information in this article or elsewhere on
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